These settings need to be changed if you have suPHP enabled on your server. It tells Softaculous to set the correct permissions for writable files and folders.
Go to settings, edit the CHMOD Files to 0644 and CHMOD Directories to 0755 (shown in the figure) and click edit settings.
Config File Settings
If you are running suPHP and would like CONFIG files to be more secure than set the CHMOD config files to the permission you wish to set. e.g. 0600 will make it readable only to the user and no one else.